Research Information System
Thesis Type: Expertise In Medicine
Institution Of The Thesis: Gazi University, Sağlık Bilimleri Enstitüsü, İç Hastalıkları Anabilim Dalı, Turkey
Approval Date: 2018
Thesis Language: Turkish
Student: Büşra YÜRÜMEZ
Supervisor: Müjde Yaşım Aktürk
Abstract:
Lifetime risk of developing diabetic foot (DF) is 15-25% in diabetes mellitus (DM). Patients with DM might have some alterations in tendons in lower extremity, which may contribute to development of DF. The purpose of our study was to investigate the alterations in tendons of foot at high risk for development of diabetic foot. Twenty-two patients with type 2 DM who have developed diabetic foot on the single foot, without any known pathology on the opposite extremity and age, sex, body mass index, shoe size similar 22 healthy volunteers were included in the study. The volume of achilles tendon (AT), cross-sectional area (CSA) of plantar fascia (PF), thickness of achilles, flexor hallucis longus, flexor digitorum longus, tibialis posterior and peroneus longus tendons, plantar fascia irregularity and edema of intrinsic foot muscle or AT were investigated using MRI. Nineteen patients with DM had PF irregularity, whereas none of the healthy controls had any irregularity (p<0.001). Intrinsic muscle edema was found to be more common in the DM group (p<0.05). AT volume and CSA of PF were decreased in patients with peripheral artery disease (PAD) compared to patients without PAD in DM group (p<0.05). DM group without PAD had higher CSA of PF compared to controls (p<0.05). There was no difference in AT volume, CSA of PF and other tendon thickness between
the groups (p>0.05). In conclusion, PF irregularity and muscle edema, may indicate high risk for development of DF. Additionally, PAD may cause alterations in tendons of foot in diabetic patients.
Key words: diabetic foot, tendon, plantar fascia, achilles, MRI