Research Information System
Thesis Type: Expertise In Medicine
Institution Of The Thesis: Gazi Üniversitesi, Tıp Fakültesi, Turkey
Approval Date: 2019
Thesis Language: Turkish
Student: ANIL GÖKÇE
Supervisor: ABDULLAH İRFAN TAŞTEPE
Abstract:The diagnosis of lung cancer is increasing every year and an average of 1.2 million new lung cancer patients are diagnosed annually worldwide. The difficulties in early detection of lung cancer and the lack of screening programs are likely to increase the incidence of patients with advanced stage tumors such as T4. In our study, 80 patients with T4 non-small cell lung cancer operated at Gazi University Department of Thoracic Surgery between January 2011 and December 2018 were included. In our retrospective study, patients who underwent lung resection and lymph node dissection were examined. In our study, the 8th TNM staging system was used for pathological staging. The presence of lymph node involvement, especially the features of T4 tumors such as tumor diameter, invasion into surrounding tissues, presence of tumor nodules in different lobes on the same side, were also used in pathological staging. The mean follow-up period of the 80 patients was 13 months and median survival was 17 months. The 2-year survival rate was %39.9 and the 5-year survival rate was %23.5. T4 tumors are still a major problem in lung cancers because of the difficulties in determining the suitability of the patients, the difficulties in their surgery, the lack of many alternatives in postoperative treatment and failure to achieve long survival times even under adjuvant therapy. With increasing surgical opportunities, advances in adjuvant chemoradiotherapy and recent successes in 124 immunotherapy treatment, it is expected to be more successful in the treatment of T4 tumors in the near future.