Research Information System
Thesis Type: Postgraduate
Institution Of The Thesis: Gazi University, Sağlık Bilimleri Enstitüsü, FİZYOTERAPİ VE REHABİLİTASYON ANA BİLİM DALI, Turkey
Approval Date: 2020
Thesis Language: Turkish
Student: FATMA BÜŞRA BENGÜBOZ
Supervisor: İlke Keser
Abstract:
The aim of this study was to investigate the effect of home physiotherapy program on toxicity, muscle
strength and endurance, balance and sensation for 12 weeks in patients diagnosed with colon cancer
for the first time. 14 patients who were diagnosed with colon cancer by applying to the Medical
Oncology Department of Gazi University Hospital and decided to undergo adjuvant chemotherapy
were included in the study.The patients were randomly divided as intervention (n:7) and control (n:7)
groups. The patients in control group were informed about chemotherapy period. The intervention
group was taught exercises and walking, balance and sensory training additionally. Physiotherapist
called patients and followed up patients every week regularly. The patients were assessed in the first
course of chemotherapy and at the 12th week. Patients muscle strength and endurance, sensory and
balance were assessed with manual muscle test, 30sec. chair stand test, Semmes Weinstein
Monoflaman test (SMWT) and aesthesiometer, one foot standing test, respectively. In the cycle of
each cure received for 12 weeks the chemotherapy related symptoms, toxicity, and blood values were
respectively measured with "Memorial Symptom Assessment Scale (MSAS)”, "NCI- Common
Terminology Criteria for Adverse Events Version 5.0" and routinly taken blood analysis were
reported. In the intervention and control groups were determinated in order of median age values
were 59(45-66) years; 63(55-74) years In comparison of the groups in the MSAS values, the
increases were determined significant in the values of the group, time, and the change of the groups
more in control group. After treatment, diarrhea, nausea, dry mouth, arthralgia and fatigue decreased
in the intervention group and increased in the control group. Decrease in Iliopsoas and Quadriceps
muscle strength in the control group, and increase in the Iliopsoas muscle strength in the intervention
group were significant. It was determined that the decrease in the control group was significant in
the onefoot test and 30sec chair stand test. In the SMWT control group, threshold values were
increased in the areas determined in the hands and feet, and sensory loss was found to be
significant.The decrease in platelet values was determined according to time and group-time
variable.Conclusion:According to the limited data, it has been observed that the physiotherapy home
program applied in the first 12 weeks of the adjuvant chemotherapy period may have positive effects
to decrease side effects of chemotherapy, prevent loss of muscle strength and endurance, balance and
sensation
Key Words : Colon Cancer, Thrombocytopenia, Neutropenia, Anemia, Exercise