Research Information System
Thesis Type: Postgraduate
Institution Of The Thesis: Gazi Üniversitesi, Fen Bilimleri Enstitüsü, Turkey
Approval Date: 2015
Student: MELTEM EMİRAL
Supervisor: YUSUF KALENDER
Open Archive Collection: AVESIS Open Access Collection
Abstract:Mercuric chloride and lead nitrate are commonly encountered environmental contaminants known to be toxic. In this study, mercuric chloride (0,02 mg/kg day), lead nitrate (45 mg/kg day) and lead nitrate+mercury chloride (45 mg/kg day lead nitrate + 0,02 mg/kg day mercury chloride) were given to male rats through gavage. 4 weeks after treatment were examined histopathological changes that occur in the lungs in rats with a light microscope and was examined in comparison with the control group. By the fourth week of lung tissue obtained at the end studied in rats administered mercury chloride emphysematous changes, mononuclear cell infiltrate, desquamation of the epithelial lining of the bronchiole and thickness in the interalveolar septum whereas emphysema and desquamation of the epithelial lining of the bronchiole were observed in the lead nitrate group. The rats are administered together, lead nitrate and mercury chloride were determined emphysema and thickness in the interalveolar septum As a result, lead nitrate and mercury chloride caused more toxic effects than other groups.