Research Information System
Thesis Type: Expertise In Medicine
Institution Of The Thesis: Gazi University, Tıp Fakültesi, Turkey
Approval Date: 2010
Thesis Language: Turkish
Student: CELAL BOZKURT
Supervisor: ALPASLAN ŞENKÖYLÜ
Abstract:Introduction The aim of this study is to design o novel lumbar interbody cage made of bioglass in the treatment of degenerative lumbar vertebrae disease and optimize the geometry of this novel cage biomechanically with finite element method (FEM) and real biomechanical tests. Materials and Methods A bioglass cage prototype made in dimensions 15,5mm x 15,5mm x 10,2mm. This cage was tested with the instron universal test machine and with FEM. Then the results are compared. After that L3-L4-L5 lumbar vertebrae are modelled by FEM. With this model intact vertebrae and the processed cages in different geometries are evaluated. By the FEM test data the appropriate cage design is determined and the cage is processed. Then these cages are tested with the Dartec test machine. The same tests are done with FEM and then the results are compared. Results Unprocessed cage is tested with the Instron testing machine. Elastic modulus value is 31,88 GPa and the maximum compression value is 121,16 MPa. Then L3- L4-L5 vertebraes are modeled with FEM. 400 N axial compression and 6 Nm moment force is applied. Under flexion, extension, bending and rotation movements the cages are evaluated and the appropriate geometry is determined. After that three unprocessed cage is processed with Challenger 2412 microcut machine. These cages are tested with Dartec testing machine. The cages are broken at 4,3 kN, 3,9 kN and 5,63 kN loadings. This test is simulated with FEM and 5 kN axial load is applied. The real and FEM test results are harmonious. Conclusions By the results of this study we have observed that the bioglass cage is found as a biomechanically compatible implant. Finally, we think that this novel cage is a promising material for the interbody fusion applications in the future. But in order to get the biocompatibility and in vivo behavior of the material, we need to test the novel cage in different animal models.