Comparison of two-dimensional transvaginal ultrasound, three-dimensional (3D) ultrasound and hysteroscopic imaging to diagnose in patients with abnormal uterine bleeding


Thesis Type: Expertise In Medicine

Institution Of The Thesis: Gazi University, Tıp Fakültesi, Turkey

Approval Date: 2020

Thesis Language: Turkish

Student: Dr. Hazal KUTLUCAN

Supervisor: NURAY BOZKURT

Abstract:

Abnormal uterine bleeding is one of the most common reasons that causes applying of patients to the gynecology outpatient clinic, and imaging methods, together with anamnesis, physical examination, labaratory examinations, are of great importance to diagnose. In this study, the success of TVUSG, three-dimensional (3D) USG and hysteroscopy were compared with gold standard histopathology. Fifty patients between ages of 20-52 who were in the reproductive period were included in the study. The condition was sought for all patients of abnormal uterine bleeding and to be applied all three methods for diagnosis. Even if no pathology was visualised during hysteroscopy, endometrial sampling was taken from all patients and evaulated histopathologically. NPD, PPD, sensitivity ve specificity values of the methods were calculated according to the gold standard method in diagnosis. The application complaint of 72% of the patients participating in the study was menorrhagia. Endometrial polyp was detected in 58% of TVUSG, %80 of 3D USG and 68% of hysteroscopy. Histopathologically, 70% of the patients had endometrial polyp. The second most common pathology was myoma uteri. While the sensitivity of detecting pathology with TVUSG was 65.85%, it was 97.56% with 3D USG and 78.04% with hysteroscopy. While TVUSG was 65.71% sensitivity in the detection endometrial polyp, 3D USG had 80% and hysteroscopy had %77,77. Hysteroscopy showed 100% sensitivity and specifity in detecting myoma uteri. When looking at all methods, although two-dimensional TVUSG is considered as the initial modality for diagnosis, new technology has achieved high sensitivity in detecting pathological leisons with three-dimensional ultrasound, and it has been observed that it is a guide preventing unnecessary invasive procedures and determining the correct hysteroscopic method before invasive procedure. Gynecologists should improve themselves in 3D USG and its use should be widespread considering it as an initial modality in the diagnosis of many diseases.