Research Information System
Thesis Type: Expertise In Medicine
Institution Of The Thesis: Gazi Üniversitesi, Tıp Fakültesi, Turkey
Approval Date: 2016
Student: MEHMET SELÇUK ŞENOL
Supervisor: AKİF MUHTAR ÖZTÜRK
Abstract:Total knee arthroplasty is a successful surgery with good results in treating end-stage knee osteoarthritis. As the ratio of the elder population and the mean life expectancy increase, this surgery is carried out more frequently in years. Total knee arthroplasty is usually applied to elder population, therefore the risk of having perioperative and postoperative complications rises. The incidences of acute kidney injury, serum electrolyte disorders and acute liver injury in 24 hours after total knee arthroplasty are analyzed. The relationship with these metabolic complications and the factors like age, gender, applying simultaneous bilateral knee arthroplasty and the type of anesthesia are elaborately assessed; and determining the patients at risk is aimed. Also, by comparing the blood biochemistry parameters right after the surgery and the next day morning after the surgery; the content and the timing of blood tests to be screened at risky patients are tried to be revealed. The 1263 patients, who were undergone total knee arthroplasty at our clinic in the years between 2011 and 2016, and diagnosed with end-stage knee degenerative arthritis were studied; and the incidences of acute kidney injury, serum electrolyte disorders and acute liver injury in 24 hours after surgery and the factors that may affect these conditions are sought. As our results, acute kidney injury is a common complication and the incidence increases with elder patients, male gender and applying simultaneous bilateral knee arthroplasty. Hyponatremia, hypopotassemia and hypocalcemia are found to be frequent electrolyte disorders and it is recommended to be diagnosed and treated when they are symptomatic. Acute liver injury is noted as a rare complication seen after total knee arthroplasty. Most of the biochemistry parameters are not disrupted in blood samples taken right after the surgery, so it is not the appropriate time to screen the patients.