Research Information System
Thesis Type: Doctorate
Institution Of The Thesis: Gazi Üniversitesi, Sağlık Bilimleri Enstitüsü, Turkey
Approval Date: 2012
Student: ZEYNEP ASLI GÜÇLÜ
Supervisor: ALEV ALAÇAM
Abstract:The aim of this clinical study is to investigate the effectiveness of fluoride varnish, CPP-ACP and CPP-ACP and fluoride varnish applications in addition to a standard remineralization protocol used for the white spot lesions development. 21 children between the ages of 8-15 on a total of 101 tooth surfaces with white spot lesion treated for 12 weeks. The patients were randomly distributed into four groups. Control group was treated for a daily procedure of remineralization protocol including oral hygiene education, chlorhexidine mouthwash and chewing-gum with xylitol. In addition to the protocol of control group, second group had fluoride varnish, third had CPP-ACP and fourth had fluoride varnish with CPP-ACP. Before and after the remineralization protocols carried out, visual and DIAGNOdent Pen scores was recorded to compare the efficiency of all procedures The results of this study has shown that CPP-ACP with varnish or without varnish was significantly higher values in the success of visual examination (p <0.001 and p<0.001). In addition, CPP-ACP groups were determined significantly higher reduction in DIAGNOdent value. CPP-ACP itself seems to have an additional benefit to standard procedure and have a potential for treating white spot lesions in this short-term study.