Research Information System
Thesis Type: Expertise In Medicine
Institution Of The Thesis: Gazi Üniversitesi, Tıp Fakültesi, Turkey
Approval Date: 2019
Thesis Language: Turkish
Student: GÖKTUĞ ÜLKÜ
Supervisor: FİKRET HÜSEYİN DOĞULU
Open Archive Collection: AVESIS Open Access Collection
Abstract:Objectives: Corpus callosum is the biggest commissural fiber bundle and connects homolog areas between two hemispheres. It’s crucial that neurosurgeons have to know corpus callosum anatomy and understand it’s connections. Material And Methods: Dissections were made at Acıbadem University Faculty of Medicine Neuroanatomy Laboratory and Gazi University Faculty Of Medicine Hızır Alp Microsurgery Laboratory between july 2019-october 2019. Ten adult human formalin-fixed cadaveric hemispheres and 4 formalin-fixed human head were examined using the fiber dissection technique. Dissections performed by surgical microscobe and surgical micro-dissection tools were used. Every step of dissections were photographed stereoscopically. The dissections were performed from lateral to medial, medial to lateral, superior to inferior, and inferior to superior. MR tractography showing corpus callosum and connected tracts aided in explaining the relationship of white matter tracts and corpus callosum. 50 Results: Microsurgical anantomy of the corpus callosum and related white matter tracts were examined by dissections and MRI tractographies. Results of the step by step dissections were; callosal fibers in coronal plane divided into three different layers. From superior to inferior first layer was; dorsal callosal fibers which connect two homolog cortical areas, second layer was intermediate callosal fibers that merges into internal capsula and the last layer of the fibers was ventral callosal fibers which provide connection between two caudate nucleus. Two new white matter tracks were identified. First white matter bundle was originating from antero-dorsal splenium and has a course through hippothalamus. Second fiber tract was originating from posterior splenium and gave fibers to cingulum and sledge runner. Also another fiber bundle which originates from antero-inferior spleniuma and merging into cingulum was identified. Callosal segmentation was revisied according to our findings about the fact that; two motor cortical areas are connects through isthmus of the corpus callosum. Conclusion: Microsurgical anatomy of the corpus callosum and related white matter tracts are important for the neurosurgery. Knowing this anatomical structure and understanding it’s connections will lead new developments for surgical interventions. And also these connections have a crucial role to understand invasion patterns of the glial tumors and disseminetion of the epileptical seizures.