Research Information System
Thesis Type: Expertise In Medicine
Institution Of The Thesis: Gazi University, Turkey
Approval Date: 2015
Thesis Language: Turkish
Student: EMRAH ÇELTİKÇİ
Supervisor: AHMET MEMDUH KAYMAZ
Abstract:Meningioma literature has many large case series which have been referrences of text books and neurosurgical practice. Many of those large series were investigated before radiosurgical practice were so often or in terms of WHO 2000 classification. In this study we aimed an update to the current literature. Between January 2007 and December 2013, 488 intracranial meningioma patients underwent open surgery. All pathological specimens reexamined by department of pathology in terms of WHO 2007 classification. All demographical records, follow up records and imaging archives were investigated by using Gazi University Hospital's central automation system and National Central Population Management System. If records were not available or enough, investigators made phone calls to patients. Pediatric patients not included to this study. 449 adult patients were eligible for analysis. 326 were female (76,2%) and 123 were male (27,4%). Age distrubution were 18 - 84 years (51,6 ± 11,9). Irrevelant from pathological subtype, patient demographic and follow up results demostrated most common subtype is meningotelial meningioma (n = 232, 51,7%), following by atypical subtype (n = 91, 20,3%). Also WHO Grade I meningiomas has statistically random localisation distrubution but WHO Grade II meningiomas are more common in convexity, parasaggital and middle fossa. Total 44 patients died, 11 of them were died in the first first month following 100 surgery or never able to discharge from intevsive care unit. Younger patient age were found significantly related with recurrence or progression. As expected WHO grade were found related with survival. Convexity found most common localisation related with mortality significantly, which is also found the most common localisation for high grade meningiomas. Mortality, localisation, patient age and pathological subtype has a relation in meningioma patients.