Research Information System
Thesis Type: Postgraduate
Institution Of The Thesis: Gazi University, Sağlık Bilimleri Enstitüsü, ODYOLOJİ VE KONUŞMA SES BOZUKLUKLARI PROGRAMI, Turkey
Approval Date: 2019
Thesis Language: Turkish
Student: ELİF TUNÇ SONĞUR
Supervisor: Metin Yılmaz
Abstract:
The main aim of the study was to determine the effect of dysphonia and disease activity on
voice in individuals with rheumatoid arthritis by objective and subjective methods.
Secondly, the effect of depression on dysphonia in individuals with rheumatoid arthritis
was determined. A total of 80 subjects (38 rheumatoid arthritis and 42 healthy volunteers
aged 18-65 years) were included in the study.Voice Handicap Index-10 (VHI-10) was
applied in order to evaluate the effect of sound on quality of life by questioning the
subjective voice complaint of the participants. The laryngeal findings were evaluated by
videolaryngoscopic evaluation of 38 rheumatoid arthritis subjects in the study group.
Maximum phonation time (MPT) measurements and acoustic sound analysis were
performed to evaluate the presence of objective dysphonia. Disease activity of individuals
with rheumatoid arthritis was determined by usingDisease Activity Score-28 (DAS28)
scale. In addition, Beck Depression Inventory (BDI) was applied to evaluate the symptoms
of depression in all participants. In order to determine the effect of disease activity and
depression on dysphonia, acoustic sound analysis was performed. According to the
evaluation results, the rate of laryngeal change in individuals with rheumatoid arthritis was
found to be %42,1. The participants in the study group were found to be lower than the
control group of the MPT (p <0.05). In our study, dysphonia complaint was found to be
%15,8 according to VHI-10. Jlocal and jrap parameters were statistically significant and
jppq and jabs parameters were found to be clinically significant in the objective voice
analysis of male participants in the study and control groups. According to DAS28, it was
found that jitter parameters increased in rheumatoid arthritis participants in remission
period compared to active participants. It was determined that 15.8% of the participants in
the study group had symptoms of depression but not related to acoustic sound parameters.
According to the findings, dysphonia complaint was higher in rheumatoid arthritis patients
compared to the control group and it was determined that male patients with rheumatoid
arthritis were more affected by acoustic sound analysis findings. There was no relationship
between depression and dysphonia in patients with rheumatoid arthritis.
Key Words : Rheumatoid arthritis, sound, dysphonia, acoustic analysis, DAS28