Clinical, biochemical and radiographic evaluation of different placement times of intraosseous implant


Thesis Type: Doctorate

Institution Of The Thesis: Gazi Üniversitesi, Sağlık Bilimleri Enstitüsü, Turkey

Approval Date: 2014

Student: HAYRİYE GÖKÇEN ALTAN

Supervisor: AYŞE EMEL ÖKTE

Abstract:

According to original protocol, a long healing period of 6-8 months is required between tooth extraction and implant placement. In order to reduce this time period, studies evaluating, immediate and early implant placement are seen. The aim of our study was to compare the clinical, biochemical and radiographic data of the 3 implant placement methods. After completing periodontal treatments, following tooth extractions, a total of 38 implants were placed immediately (Group 1), at 4-6 weeks (Group 2) and at minimum 6 months (Group 3) to 18 patients. Plaque index, gingival index, probing depth and bleeding on probing scores were recorded from tooth and implants at baseline, after periodontal treatment, at implant loading time (accepted as zero month) and at 1, 3, 6, 12 months after loading. Radiographic examination were performed at 0, 6 and 12 months after loading and at the same time period, peri implant crevicular fluid samples were obtained, OPG and RANKL levels were assessed with ELİSA method. All full mouth periodontal parameters were reduced significantly after periodontal treatments compared to baseline (p<0.05) and no statistically significant increase was observed at 0 to 12 month period (p>0.05). For Groups 1, 2 and 3, mean scores of modified plaque index were 0.37, 0,.22, 0.17, modified gingival index were 0.96, 0.89, 0.95, probing depth were 2,3 mm, 2,61 mm, 2,34 mm and bleeding on probing were 15.61%, 26.65%, 18.86%, respectively. No statistically significant differences were observed between groups at 0 to 12 months (p>0.05). Radiographic bone loss was observed as 1.03 mm for Group 1, 0.6 mm for Group 2 and 0.48 mm for Group 3 after 12 months. Statistically significant decrease with regard to concentration and total amount of OPG was observed only in Group 3 at 0 to 12 month period (p<0.05) . OPG concentration, OPG total amount and RANKL concentration levels did not show any significant difference between groups (p>0,05). Our results show that immediate, early and late implant placement protocols were inclusive of success criteria after 12 months.