Erosive effect assessment of vitamin and iron preparations used in early childhood

ZEYNEP BERCİS BAŞAK

Erosive effect assessment of vitamin and iron preparations used in early childhood

Thesis Type: Doctorate

Institution Of The Thesis: Gazi Üniversitesi, Sağlık Bilimleri Enstitüsü, Turkey

Approval Date: 2013

Student: ZEYNEP BERCİS BAŞAK

Supervisor: CENGİZ HALUK BODUR

Open Archive Collection: AVESIS Open Access Collection

Abstract:

This study aimed to evaluate the effect of an oral liquid multivitamin and iron preparations on roughness, microhardness and topography of primary enamel and the influence of pH and titratable acidity on its erosive effect, if any. Ninety-one enamel blocks prepared from exfoliated primary teeth. Enamel blocks were divided into seven groups according to media immersion: three iron formulations (Ferro-sanol, Ferrum, FerroZinc), four multivitamin formulations (Vitabiol, Devit-3, ACD3, Multi-tabs). The samples were exposed to two pH cycles everyday and kept in artificial saliva for 14 days. The surface roughness, microhardness measurements, elemental and topographic analysis of the enamel specimens were done. Data were analyzed by the Kruskal-Wallis or ANOVA test. Exposure to the seven different preparations resulted in the loss of enamel roughness between 0.2 and 2.3 microns of primary enamel. With regard to roughness and microhardness, Ferro-sanol, Ferrum and Vitabiol, Devit-3, ACD3 were lead to a significant results (p<0.05) after pHcycling regimens. When compared to sound primary enamel, qualitative analysis of SEM micrographs showed that specimens exposed to Ferro-sanol and Vitabiol presented the most severely eroded areas, followed by those exposed to other preparations. In the EDS area scan difference between the control and study group, highest reducing weight percentage of surface phosphor was observed for the samples treated with the Ferro-sanol but this was not statistically significant (p>0,05). In groups of Ferro-sanol, Ferrum, Vitabiol, Devit-3 ve ACD3 calcium content was significantly lower than control groups. Weight percentages of calcium in these five groups showed statistically significantly difference ( p<0,05). It was concluded that the iron or multivitamin preparations were effected the microhardness, roughness, elemental weight of primary enamel and that, in this experiment, the lower pH and the higher titration were influence the erosive effect.