Doç. Dr. PELİN TELKOPARAN AKILLILAR | AVESİS

Akademik Veri Yönetim Sistemi

Yayınlar & Eserler

Makaleler 37

1. Design, synthesis, computational insights, and evaluation of tetrazole containing donepezil derivatives as antibiofilm, antimicrobial, and anticancer agents with doxorubicin

DİŞLİ A., Aksu E., DOYDUK D., Akdogan N., Cuhaci U., Ozadam N., et al.

JOURNAL OF MOLECULAR STRUCTURE , cilt.1349, 2026 (SCI-Expanded)

2. An overview of insights and updates on TTN mutations in cardiomyopathies

Saha S., Temaj G., Telkoparan Akıllılar P., Chichiarelli S., Saso L.

FRONTIERS IN PHARMACOLOGY , cilt.15, sa.1668544, ss.1-10, 2025 (SCI-Expanded)

3. Polyploid giant cancer cells: Underlying mechanisms, signaling pathways, and therapeutic strategies

Temaj G., Saha S., Chichiarelli S., TELKOPARAN AKILLILAR P., Nuhii N., Hadziselimovic R., et al.

Critical Reviews in Oncology/Hematology , cilt.213, 2025 (SCI-Expanded)

4. Therapeutic potential of alpha-pinene in methotrexate-induced testicular toxicity: focus on apoptosis, oxidative stress, and inflammatory pathways

Kabartan E., Cirrik S., Hacioglu G., Tezcan Yavuz B., TELKOPARAN AKILLILAR P., Sirin Tomruk C.

Naunyn-Schmiedeberg's Archives of Pharmacology , 2025 (SCI-Expanded)

5. 7,8‑dihydroxyflavone reduces lipid peroxidation, proinflammatory cytokines, and mediators in chemically induced‑phenylketonuria model.

Cicek C., TELKOPARAN AKILLILAR P.

Acta neurobiologiae experimentalis , cilt.84, sa.3, ss.243-255, 2024 (SCI-Expanded)

6. Investigation of endoplasmic reticulum stress-regulated chaperones as biomarkers in idiopathic nonobstructive azoospermia

Cicek C., TELKOPARAN AKILLILAR P., Sertyel S., Bilgi C., Ozgun O. D.

Cell Stress and Chaperones , cilt.29, sa.5, ss.654-665, 2024 (SCI-Expanded)

7. P53: A key player in diverse cellular processes including nuclear stress and ribosome biogenesis, highlighting potential therapeutic compounds

Temaj G., Chichiarelli S., TELKOPARAN AKILLILAR P., Saha S., Nuhii N., Hadziselimovic R., et al.

Biochemical Pharmacology , cilt.226, 2024 (SCI-Expanded)

8. Advances in molecular function of UPF1 in Cancer

Temaj G., Chichiarelli S., TELKOPARAN AKILLILAR P., Saha S., Nuhii N., Hadziselimovic R., et al.

Archives of Biochemistry and Biophysics , cilt.756, 2024 (SCI-Expanded)

9. Redox Homeostasis and Nrf2-Regulated Mechanisms Are Relevant to Male Infertility

Signorini C., Saso L., Ghareghomi S., Telkoparan-Akillilar P., Collodel G., Moretti E.

Antioxidants , cilt.13, sa.2, 2024 (SCI-Expanded)

Creative Commons License

10. Proteomics analysis identifies the ribosome associated coiled-coil domain-containing protein-124 as a novel interaction partner of nucleophosmin-1

Çakırca G., Öztürk M. T., Telkoparan-Akillilar P., Güllülü Ö., Çetinkaya A., Tazebay U. H.

Biology of the Cell , cilt.116, sa.1, 2024 (SCI-Expanded)

11. Identification of differentially expressed miRNAs and mRNAs associated with the regulation of breast cancer via in silico and in vitro methods

Telkoparan-Akillilar P., Cevik D.

Cytotechnology , cilt.75, sa.5, ss.363-379, 2023 (SCI-Expanded)

12. 7,8-Dihydroxyflavone decreases lipid peroxidation and proinflammatory cytokines in the phenylketonuria

Cicek C., Telkoparan-Akillilar P.

FEBS OPEN BIO , cilt.13, ss.190, 2023 (SCI-Expanded)

13. NRF2, a crucial modulator of skin cells protection against vitiligo, psoriasis, and cancer

Panieri E., Telkoparan-Akillilar P., Saso L.

BioFactors , cilt.49, sa.2, ss.228-250, 2023 (SCI-Expanded)

14. Recoding of Nonsense Mutation as a Pharmacological Strategy

Temaj G., Telkoparan-Akillilar P., Nuhii N., Chichiarelli S., Saha S., Saso L.

Biomedicines , cilt.11, sa.3, 2023 (SCI-Expanded)

15. Clitocybe nebularis extract and 5‑fluorouracil synergistically inhibit the growth of HT-29 colorectal cancer cells by inducing the S phase arrest

ONAR O., Telkoparan-Akillilar P., YILDIRIM Ö.

3 Biotech , cilt.13, sa.2, 2023 (SCI-Expanded)

16. Interplay between Non-Coding RNAs and NRF2 in Different Cancers: Spotlight on MicroRNAs and Long Non-Coding RNAs

YAYLIM İ., Farooqi A. A., Telkoparan-Akillilar P., Saso L.

Journal of Pharmacology and Experimental Therapeutics , cilt.384, sa.1, ss.28-34, 2023 (SCI-Expanded)

17. An Overview of NRF2-Activating Compounds Bearing α,β-Unsaturated Moiety and Their Antioxidant Effects

Egbujor M. C., Buttari B., Profumo E., Telkoparan-Akillilar P., Saso L.

International Journal of Molecular Sciences , cilt.23, sa.15, 2022 (SCI-Expanded)

18. cAMP/PKA-CREB-BDNF signaling pathway in hippocampus of rats subjected to chemically-induced phenylketonuria

Cicek C., EREN KOÇAK E., Telkoparan-Akillilar P., Gok M., BODUR E.

Metabolic Brain Disease , cilt.37, sa.2, ss.545-557, 2022 (SCI-Expanded)

19. Expression patterns of miR-34a, miR-125b, miR-221 and antioxidant gene NRF2 in plasma samples of patients with atherosclerosis.

Telkoparan-Akillilar P., Cevik D., Yilmaz A.

Journal of biosciences , cilt.47, 2022 (SCI-Expanded)

20. Identification of miR-17, miR-21, miR-27a, miR-106b and miR-222 as endoplasmic reticulum stress-related potential biomarkers in circulation of patients with atherosclerosis

Telkoparan-Akillilar P., Cevik D.

Molecular Biology Reports , cilt.48, sa.4, ss.3503-3513, 2021 (SCI-Expanded)

21. Therapeutic targeting of the NRF2 signaling pathway in Cancer

Telkoparan-Akillilar P., Panieri E., Cevik D., SÜZEN S., Saso L.

Molecules , cilt.26, sa.5, 2021 (SCI-Expanded)

22. Coiled-coil domain-containing protein-124 (Ccdc124) is a novel RNA binding factor up-regulated in endometrial, ovarian, and urinary bladder cancers

Arslan Ö., Soylu N. K., Akillilar P., Tazebay U. H.

Cancer Biomarkers , cilt.31, sa.2, ss.149-164, 2021 (SCI-Expanded)

23. The applications of next-generation sequencing (Ngs) in drug development for cancer therapy

Telkoparan-Akillilar P., Cevik D.

Current Analytical Chemistry , cilt.17, sa.8, ss.1074-1081, 2021 (SCI-Expanded)

24. Investigation of Some Inflammation Related Gene Expressions Under Lipotoxic Endoplasmic Reticulum Stress In Mouse Macrophage Cell Line

TELKOPARAN AKILLILAR P.

Acıbadem Üniversitesi Sağlık Bilimleri Dergisi , cilt.4, ss.607-614, 2020 (Hakemli Dergi)

25. The nrf2/keap1 axis in the regulation of tumor metabolism: Mechanisms and therapeutic perspectives

Panieri E., Telkoparan-Akillilar P., SÜZEN S., Saso L.

Biomolecules , cilt.10, sa.5, 2020 (SCI-Expanded)

26. Potential applications of NRF2 modulators in cancer therapy

Panieri E., Buha A., Telkoparan-akillilar P., Cevik D., Kouretas D., Veskoukis A., et al.

Antioxidants , cilt.9, sa.3, 2020 (SCI-Expanded)

27. Pharmacological applications of Nrf2 inhibitors as potential antineoplastic drugs

Telkoparan-Akillilar P., SÜZEN S., Saso L.

International Journal of Molecular Sciences , cilt.20, sa.8, 2019 (SCI-Expanded)

28. Anticancer, Antioxidant Properties and Phenolic, Flavonoid Composition of Heracleum platytaenium Plant Methanolic Extracts

TELKOPARAN AKILLILAR P., Tuğlu Y. B., Shomali Moghaddam N.

JOURNAL OF RESEARCH IN PHARMACY , cilt.22, sa.1, ss.69-77, 2018 (Scopus)

29. Role of Circulating Tumor Cells and Cell-Free Tumor Deoxyribonucleic Acid Fragments as Liquid Biopsy Materials in Breast Oncology

TELKOPARAN AKILLILAR P., YILDIZ G.

TURK ONKOLOJI DERGISI , cilt.32, ss.35-41, 2017 (Scopus)

30. Targeting IRE1 with small molecules counteracts progression of atherosclerosis

Tufanli O., Akillilar P., Acosta-Alvear D., Kocaturk B., ONAT U. İ., Hamid S. M., et al.

Proceedings of the National Academy of Sciences of the United States of America , cilt.114, sa.8, 2017 (SCI-Expanded)

31. DNA Damage Repair and Related Human Diseases

TELKOPARAN AKILLILAR P., YILDIZ G.

Koruproceedings , 2016 (Hakemli Dergi)

32. Coiled-Coil Domain Containing Protein 124 Is a Novel Centrosome and Midbody Protein That Interacts with the Ras-Guanine Nucleotide Exchange Factor 1B and Is Involved in Cytokinesis

Telkoparan P., Erkek S., Yaman E., ALOTAİBİ H., Bayik D., Tazebay U. H.

PLoS ONE , cilt.8, sa.7, 2013 (SCI-Expanded)

Creative Commons License

33. Iodine in milk: transport, metabolic implications, and relation to endocrine functions

Telkoparan P., Tazebay U. H.

HANDBOOK OF DIETARY AND NUTRITIONAL ASPECTS OF HUMAN BREAST MILK , sa.5, ss.371-385, 2013 (SCI-Expanded) Sürdürülebilir Kalkınma

Sürdürülebilir Kalkınma

34. Ras family of proteins: Cellular function, molecular control, and its role in oncogenesis Ras protein ailesi: Hücresel i̇şlevi, moleküler kontrolü, onkogenezdeki rolü

Telkoparan P., Tazebay U. H.

Turkish Journal of Biochemistry , cilt.36, sa.4, ss.367-373, 2011 (SCI-Expanded)

35. Ras Family of Proteins: Cellular Function, Molecular Control, and its Role in Oncogenesis

TELKOPARAN AKILLILAR P., Tazebay U. H.

TURKISH JOURNAL OF BIOCHEMISTRY-TURK BIYOKIMYA DERGISI , cilt.36, sa.4, ss.367-373, 2011 (SCI-Expanded) Sürdürülebilir Kalkınma

Sürdürülebilir Kalkınma

36. The ability to generate senescent progeny as a mechanism underlying breast cancer cell heterogeneity

Mumcuoglu M., Bagislar S., Yuzugullu H., Alotaibi H., Senturk S., Telkoparan P., et al.

PLoS ONE , cilt.5, sa.6, 2010 (SCI-Expanded)

Creative Commons License

37. Intronic elements in the Na+/I- symporter gene (NIS) interact with retinoic acid receptors and mediate initiation of transcription

ALOTAİBİ H., Yaman E., Salvatore D., di Dato V., Telkoparan P., di Lauro R., et al.

Nucleic Acids Research , cilt.38, sa.10, ss.3172-3185, 2010 (SCI-Expanded)

Creative Commons License

Hakemli Bilimsel Toplantılarda Yayımlanmış Bildiriler 22

1. Evaluation of the effects of sulforaphane on hepatocellular carcinoma cell lines

ÇEVİK D., TELKOPARAN AKILLILAR P., AKSOY Z.

49th FEBS Congress, İngiltere, 05 Temmuz 2025, (Özet Bildiri)

2. Potential miRNA Biomarkers Associated with the Endoplasmic Reticulum Stress Response in Ovarian Cancer: A Bioinformatics Analysis

Özgür Ş., Telkoparan Akıllılar P.

11TH INTERNATIONAL ARTEMIS SCIENTIFIC RESEARCH CONGRESS, Bucuresti, Romanya, 28 Şubat - 01 Mart 2025, ss.238-249, (Tam Metin Bildiri)

3. MicroRNAs and NRF2: Mastering the Balance of Cellular Defense in Breast Cancer and Unlocking New Therapeutic Pathways

TELKOPARAN AKILLILAR P.

13th International Conference on Business, Technology and Innovation 2024, Prishtina, Sırbistan, 25 - 27 Ekim 2024, ss.292, (Özet Bildiri)

4. Gbm'de Değişen Mirna Ekspresyonlarının ve Pı3k-Akt Sinyal Yolağındaki Rollerinin İn Siliko Analiz Yoluyla Keşfi

Telkoparan Akıllılar P., Çiçek Ç.

17th International Medicine and Heath Sciences Researches Congress, Ankara, Türkiye, 19 - 20 Ekim 2024, ss.161-162, (Özet Bildiri)

5. Innovative Strategies for Breast Cancer: Inhibiting IRE1 RNase activity and Modulating miRNAs in Triple-Negative and Receptor-Positive Breast

Telkoparan Akıllılar P., Çevik D., Perktaş N.

Moleküler Biyoloji Derneği 9. Uluslararası Kongresi', İzmir, Türkiye, 12 - 14 Eylül 2024, ss.64, (Özet Bildiri)

6. Üçlü negatif meme kanserinde Endoplazmik retikulum sensor protein IRE1'nın RNAz aktivitesine bağımlı miRNA'ların ve hedef genlerin belirlenmesi

TELKOPARAN AKILLILAR P., Perktaş N., ÇEVİK D.

18. Tıbbi Biyoloji ve Genetik Kongresi, Ankara, Türkiye, 26 Ekim 2023, (Özet Bildiri)

7. Understanding The Crosstalk Between Endoplasmic Reticulum Stress And Oxidative Stress In Diseases

TELKOPARAN AKILLILAR P.

12th Annual International Conference Pharmaceutical and Natural Sciences, Prishtina, Sırbistan, 28 Ekim 2023, (Özet Bildiri)

8. Evaluation of the suitability of serum-infrared spectroscopy combined with multivariate analysis tools for the diagnosis of atherosclerosis

YONAR D., ÇEVİK D., TELKOPARAN AKILLILAR P.

5th International/34th National BiophysicsCongress, İzmir, Türkiye, 6 - 09 Eylül 2023, ss.215-216, (Özet Bildiri)

9. Posters

ÇİÇEK Ç., TELKOPARAN AKILLILAR P.

47th FEBS Congress, July 8–12, 2023, Tours, France, Tours, Fransa, 08 Temmuz 2023, cilt.13, ss.61-258, (Özet Bildiri)

10. Ccdc124 İfadesinin Azaltılmasının Zebra Balığı Embriyolarındaki Etkileri

TELKOPARAN AKILLILAR P., TAZEBAY U. H.

11. ULUSAL MOLEKÜLER BİYOLOJİ VE BİYOTEKNOLOJİ KONGRESİ. 8 Ekim 2022, Türkiye, 08 Ekim 2022, (Özet Bildiri)

11. Expression Changes of MicroRNAs as a Result of IRE1-RNase Domain Inhibition in MDA-MB-231 Cells

Perktaş N., TELKOPARAN AKILLILAR P., ÇEVİK D.

8th International Congress of the Molecular Biology Association of Turkey., İstanbul, Türkiye, 09 Haziran 2022, (Özet Bildiri)

12. Meme kanseri tanı ve tedavisi için olası anahtar mikroRNA’lar ve hedef genlerin etkilediği moleküler mekanizmaların in silico analiz yöntemleriyle belirlenmesi

TELKOPARAN AKILLILAR P.

17. Tıbbi Biyoloji ve Genetik Kongresi 28-31 Ekim 2021, Türkiye, 28 - 31 Ekim 2021, (Özet Bildiri)

13. Analysis Of The Role Of Endoplasmic Reticulum Stress Sensor Proteins In Breast Cancer Via In Silico Methods

TELKOPARAN AKILLILAR P.

Uluslararası Bilimsel Araştırmalar ve Yenilikçi Çalışmalar Sempozyumu (International Symposium of Scientific Research and Innovative Studies), Türkiye, 22 - 25 Şubat 2021, (Özet Bildiri)

14. Palmitat ile Muamele Edilen Kemik İliği Kaynaklı Makrofajların RNA-seq Transkriptom Analizi

TELKOPARAN AKILLILAR P., ERBAY E.

XVI. TIBBİ BİYOLOJİ ve GENETİK KONGRESİ, Muğla, Türkiye, 27 - 30 Ekim 2019, (Özet Bildiri)

15. Learning and memory mechanism in Phenylketonuria with BDNF pathway

ÇİÇEK Ç., GÖK M., EREN KOÇAK E., TELKOPARAN AKILLILAR P., BODUR E.

THE 44th FEBS CONGRESS, İsrail, 6 - 11 Temmuz 2019, (Özet Bildiri)

16. Inositol- Requiring Enzyme 1 (Ire1) Inhibitor, Stf-083010, Downregulates Proatherogenic Gene Expression in Bone Marrow Derived Macrophages

TELKOPARAN AKILLILAR P., Tufanli O., Acosta Alvear D., Walter P., ERBAY E.

12th International Symposium on Pharmaceutical Sciences (ISOPS), Ankara, Türkiye, 26 Haziran 2018 - 29 Haziran 2019, (Özet Bildiri)

17. Karaciğer kanseri hücrelerinin ilaç muamelesine hassasiyetle ilişkili moleküller ağı

YILDIZ G., TELKOPARAN AKILLILAR P.

24. Ulusal Farmakoloji Kongresi, Trabzon, Türkiye, 17 - 20 Ekim 2017, (Özet Bildiri)

18. Investigation on potential roles of centrosomal protein Ccdc124 in DNA damageresponse

TELKOPARAN AKILLILAR P., Bayık D., TAZEBAY U. H.

12. Ulusal TIBBİ GENETİK KONGRESİ, Türkiye, 5 - 09 Ekim 2016, (Özet Bildiri)

19. The effect of Heracleum platytaenium plant on breast cancer and thedetermination of the amount of some phenolic-flovonoid compoundsand enzyme activity

Tuglu Y., TELKOPARAN AKILLILAR P., Shomali N.

BEWS2017, Türkiye, 3 - 05 Mayıs 2017, (Özet Bildiri)

20. Inositol requiring enzyme 1 IRE1 dependent RNAsequencing mediated transcriptome analysis of mouse bone marrow derivedmacrophages BMDM

TELKOPARAN AKILLILAR P., yagbasan b., ERBAY E.

14.Ulusal Tıbbi Biyoloji ve Genetik Kongresi, Muğla, Türkiye, 28 - 31 Ekim 2015, (Özet Bildiri)

21. Ccdc124 Proteininin Ökaryotik Hücre Bölünmesindeki Rolü

TELKOPARAN AKILLILAR P.

14. Tıbbi Biyolojive Genetik kongresi Fethiye, Türkiye, 27 - 30 Ekim 2015, (Özet Bildiri)

22. Hücre bölünmesinde rol oynayan yeni bir sentrozom ve orta cisimcik midbody proteini olan coiled coil domain containing protein 124 Ccdc124 ün moleküler karakterizasyonu

TELKOPARAN AKILLILAR P., ERKEK ÖZHAN S., ALOTAİBİ H., YAMAN E., TAZEBAY U. H.

13. Ulusal Tıbbi Biyoloji ve Genetik Kongresi (Kuşadası), Türkiye, 28 - 31 Ekim 2013, (Özet Bildiri)

Kitaplar 3

1. MikroRNA’ların Meme Kanserinin Tanı ve Takibinde Kullanımı

TELKOPARAN AKILLILAR P.

HÜCRESEL TIP VE MEDIKAL BIYOTEKNOLOJI UYGULAMALARI, Can ÖZLÜ, Nilüfer KÖYLÜOĞLU, Aysun ÖZLÜ, Hilmi Sefa YANGAL, Mehmet Ali GEDİK, Editör, Akademisyen Kitabevi A.Ş., ss.1, 2021

2. Endoplazmik Retikulum Stres ve Katlanmamış Protein Yanıtının AterosklerozGelişimindeki Rolü

TELKOPARAN AKILLILAR P.

Sağlık BilimleriÖrnek Araştırmalar Kitabı, Prof. Dr. İnci Gülmez, Öğr. Gör. Dr. Duygu Sevim, Editör, NOBEL AKADEMİK YAYINCILIK, Ankara, ss.621-633, 2019

3. Iodine in milk: transport, metabolic implications, and relation to endocrine functions

TELKOPARAN AKILLILAR P., TAZEBAY U. H.

Handbook of dietary and nutritional aspects of human breast milk, Sherma Zibadi, Ronald Ross Watson, Victor R. Preedy, Editör, Wageningen Academic Publisher, ss.371-387, 2013

Metrikler

Yayın

65

Yayın (WoS)

39

Yayın (Scopus)

37

Atıf (WoS)

934

H-İndeks (WoS)

14

Atıf (Scopus)

884

H-İndeks (Scopus)

14

Atıf (Scholar)

884

H-İndeks (Scholar)

14

Atıf (TrDizin)

2

H-İndeks (TrDizin)

1

Proje

15

Tez Danışmanlığı

4

Açık Erişim

4

BM Sürdürülebilir Kalkınma Amaçları