Challenge-proven nonsteroidal anti-inflammatory drug hypersensitivity in children
ALLERGY, vol.68, no.12, pp.1555-1561, 2013 (SCI-Expanded, Scopus)
- Publication Type: Article / Article
- Volume: 68 Issue: 12
- Publication Date: 2013
- Doi Number: 10.1111/all.12266
- Journal Name: ALLERGY
- Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
- Page Numbers: pp.1555-1561
- Keywords: drug allergy, pediatrics, PROVOCATION TESTS, NSAID HYPERSENSITIVITY, COX-2 INHIBITORS, PARACETAMOL, DIAGNOSIS, MELOXICAM, SAFETY, IGE
- Gazi University Affiliated: Yes
Abstract
BackgroundFew studies investigated hypersensitivity to nonsteroidal anti-inflammatory drugs (NSAIDs) in children. The objective was to determine the frequency of true NSAID hypersensitivity (NSAID-H) and whether there were any parameters in the history of children that would predict NSAID-H. Secondly, an investigation was conducted into whether NSAID-hypersensitive children could tolerate safe alternatives. Differing from previous studies, the researchers followed the recent diagnostic algorithm proposed for acute reactions in NSAID-H.