CHANGES IN GASTRIC-MUCOSAL HISTAMINE AND PROSTAGLANDIN -E(2)-LIKE ACTIVITIES IN RELATION TO PORTAL SOMATOSTATIN FOLLOWING SMALL-BOWEL RESECTION IN GUINEA-PIGS

ENGIN, A; ATLAN, N; ERCAN, ZS; ERSOY, E; DEMIRAG, A

doi:10.1016/0952-3278(93)90223-j

CHANGES IN GASTRIC-MUCOSAL HISTAMINE AND PROSTAGLANDIN -E(2)-LIKE ACTIVITIES IN RELATION TO PORTAL SOMATOSTATIN FOLLOWING SMALL-BOWEL RESECTION IN GUINEA-PIGS

Atıf İçin Kopyala

ENGIN A., ATLAN N., ERCAN Z., ERSOY E., DEMIRAG A.

PROSTAGLANDINS LEUKOTRIENES AND ESSENTIAL FATTY ACIDS, cilt.48, sa.4, ss.319-321, 1993 (SCI-Expanded)

Yayın Türü: Makale / Tam Makale
Cilt numarası: 48 Sayı: 4
Basım Tarihi: 1993
Doi Numarası: 10.1016/0952-3278(93)90223-j
Dergi Adı: PROSTAGLANDINS LEUKOTRIENES AND ESSENTIAL FATTY ACIDS
Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
Sayfa Sayıları: ss.319-321
Gazi Üniversitesi Adresli: Hayır

Özet

The effects of 85% intestinal resection on the portal somatostatin (SLI) gastric mucosal histamine (HA) and prostaglandin E2 (PGE2)-like activities were studied in guinea-pigs. A considerable increase in gastric mucosal HA-like activity of guinea-pigs subjected to small bowel resection (189.9 +/- 15.0 ng/g tissue) was measured in comparison to control values (42.9 +/- 6.3 ng/g tissue) (p < 0.001). The mean tissue PGE2-like activity in the sham operated group was 1636.9 +/- 128.8 ng/g tissue, whereas in the test group it was 650.5 +/- 59.3 ng/g tissue. After 85% small bowel resection a significant fall in portal and systemic venous SLI values was observed (T = 0, p < 0.05).