Polymorphisms related to estrogen and xenobiotic metabolism in healthy Turkish women

Kocabas N., Sardas S., Karakaya A.

ARCHIVES OF MEDICAL RESEARCH, cilt.36, sa.1, ss.19-23, 2005 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 36 Sayı: 1
  • Basım Tarihi: 2005
  • Doi Numarası: 10.1016/j.arcmed.2004.10.003
  • Dergi Adı: ARCHIVES OF MEDICAL RESEARCH
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.19-23
  • Gazi Üniversitesi Adresli: Hayır

Özet

Background. Polymorphisms which are inherited alterations in the activity of cytochrome P450 1B1 (CYP1B1), catechol O-methyltransferase (COMT), manganese superoxide dismutase (MnSOD) hold the potential to define differences in estrogen metabolism and, thereby, possibly explain inter-individual differences in cancer susceptibility associated with estrogen-mediated carcinogenesis.