CEPHALALGIA, vol.31, no.5, pp.537-542, 2011 (Journal Indexed in SCI)
Article / Article
Title of Journal :
Cortical spreading depression, migraine, oxcarbazepine, valproate, MIGRAINE PROPHYLAXIS, NEUROPATHIC PAIN, RAT, CARBAMAZEPINE, VALPROATE, DAMAGE, MODEL
Background: Cortical spreading depression is the electrophysiological substrate of migraine aura, and may trigger headache. Recently, chronic treatment with five migraine prophylactic drugs was shown to suppress cortical spreading depression, implicating spreading depression as a common therapeutic target in migraine prophylaxis.