Effect of 3-aminobenzamide on perforation an experimental colitis model

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Menekse E., Aydin S., SEPİCİ DİNÇEL A., Eroglu A., DOLAPÇI M., Yildirim O., ...More

TURKISH JOURNAL OF GASTROENTEROLOGY, vol.25, pp.86-91, 2014 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 25
  • Publication Date: 2014
  • Doi Number: 10.5152/tjg.2014.4288
  • Journal Name: TURKISH JOURNAL OF GASTROENTEROLOGY
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus, TR DİZİN (ULAKBİM)
  • Page Numbers: pp.86-91
  • Keywords: Poly (ADP-ribose) polymerase/synthetase inhibitor, 3-aminobenzamide, colitis, inflammatory bowel disease, INFLAMMATORY-BOWEL-DISEASE, BACTERIAL TRANSLOCATION, NEUTROPHIL RECRUITMENT, OXIDATIVE STRESS, CROHNS-DISEASE, INHIBITION, TARGET, DAMAGE, RAT
  • Gazi University Affiliated: Yes

Abstract

Background/Aims: The anti-inflammatory activity of 3-aminobenzamide (3-AB) has been shown via histopathology and immunohistochemistry in various colitis models. We aimed to study the effects of 3-AB on tissue mechanical endurance and, associatively, preventing perforation in colitis.