The Late Effects of Anticancer Therapy after Childhood Wilms Tumor: The Role of Diastolic Function and Ambulatory Blood Pressure Monitoring


Elli M., Sungur M., GENÇ G., Ayyildiz P., Dagdemir A., PINARLI F. G., ...More

JAPANESE JOURNAL OF CLINICAL ONCOLOGY, vol.43, no.10, pp.1004-1011, 2013 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 43 Issue: 10
  • Publication Date: 2013
  • Doi Number: 10.1093/jjco/hyt105
  • Journal Name: JAPANESE JOURNAL OF CLINICAL ONCOLOGY
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.1004-1011
  • Keywords: Wilms tumor, late effects, ambulatory blood pressure monitoring, diastolic functions, pulmonary venous flow, ACUTE LYMPHOBLASTIC-LEUKEMIA, CONGESTIVE-HEART-FAILURE, UNILATERAL NEPHRECTOMY, RENAL-FUNCTION, ANTHRACYCLINE THERAPY, CARDIAC-OUTPUT, RISK-FACTORS, CHILDREN, HYPERTENSION, ADOLESCENTS
  • Gazi University Affiliated: Yes

Abstract

Wilms tumor, or nephroblastoma, is the most common primary malignant renal tumor of childhood. The excellent outcome now expected for most children with this tumor is attributed to the combination of effective adjuvant chemotherapy, improved surgical and anesthetic techniques and also the radiosensitivity of the tumor. The numerous organ systems are subject to the late effects of anticancer therapy. The aim of this study was to investigate the blood pressure profile and ambulatory blood pressure monitoring, and also cardiac diastolic functions and pulmonary venous flow in 25 children with unilateral Wilms tumor in remission.