Clinical Significance of HER2 Overexpression in Gastric and Gastroesophageal Junction Cancers


Baykara M., Benekli M., EKİNCİ Ö., Irkkan S. C., Karaca H., Demirci U., ...More

JOURNAL OF GASTROINTESTINAL SURGERY, vol.19, no.9, pp.1565-1571, 2015 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 19 Issue: 9
  • Publication Date: 2015
  • Doi Number: 10.1007/s11605-015-2888-y
  • Journal Name: JOURNAL OF GASTROINTESTINAL SURGERY
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.1565-1571
  • Keywords: GC, GEJCs, HER2, Prognosis, C-ERBB-2 PROTEIN EXPRESSION, C-ERB B-2, PROGNOSTIC-SIGNIFICANCE, GENE AMPLIFICATION, CLINICOPATHOLOGICAL FEATURES, GROWTH, TRASTUZUMAB, CARCINOMAS, SURVIVAL, ADENOCARCINOMA
  • Gazi University Affiliated: Yes

Abstract

In this study, we investigated the rate of human epidermal growth factor receptor 2 (HER2) overexpression in gastric (GC) and gastroesophageal junction cancers (GEJCs) and the relationship with HER2 expression and clinical, pathological parameters and prognosis.