Determination and Role of Epstein-Barr Virus in Patients With Lymphoproliferative Disorders.

Colak M., Sarzhanova S., Yegin Z. A., Ozkurt Z. N., Fidan I., Bozdayi G.

Clinical lymphoma, myeloma & leukemia, vol.21, no.5, 2021 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 21 Issue: 5
  • Publication Date: 2021
  • Doi Number: 10.1016/j.clml.2021.01.023
  • Journal Name: Clinical lymphoma, myeloma & leukemia
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus, CINAHL, EMBASE, MEDLINE
  • Keywords: Acute lymphoblastic leukemia (ALL), EBV, Lymphoma, Real-time PCR, Real-time polymerase chain reaction, INFECTION, LEUKEMIA, LOAD
  • Gazi University Affiliated: Yes

Abstract

Many studies describe an association between Epstein-Barr virus and lymphoproliferative disorders, especially lymphomas and acute lymphoblastic leukemia (ALL). Because of the delay or lack of adequate in immune response among these patients, serologic tests can lead to false-negative results. Real-time PCR testing of patients being admitted with lymphoproliferative disorders, especially those diagnosed as ALL and lymphomas, is useful during follow-up and treatment.