Polymorphisms in the vitamin D receptor gene and risk of lung cancer

Doğan İ., Önen H. İ., Yurdakul A. S., Konaç E., Öztürk C., Varol A., ...More

MEDICAL SCIENCE MONITOR, vol.15, 2009 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 15
  • Publication Date: 2009
  • Journal Name: MEDICAL SCIENCE MONITOR
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Keywords: VDR, genetic polymorphisms, lung cancer, POSTMENOPAUSAL BREAST-CANCER, PROSTATE-CANCER, VDR GENE, ASSOCIATION, EPIDEMIOLOGY, PROGRESSION, EXPRESSION, HAPLOTYPES, CARCINOMA, GENOTYPE
  • Gazi University Affiliated: Yes

Abstract

Background: Differences between the individual variations in DNA may modulate lung cancer process. Many studies reported that Vitamin D Receptor (VDR) gene polymorphisms may influence the cancer risk due to their antiproliferative, antiangiogenic, antimetastatic and apoptoic effects.