Safety tests on mice with Bacillus thuringiensis isolate.

Çakmakçı L., Özer A. N., Alten S. B., Bor N., Yörükhan S., Boşgelmez A., ...More

Journal of Islamic Academy of Sciences, vol.3, no.1, pp.35-40, 1990 (Peer-Reviewed Journal)

  • Publication Type: Article / Article
  • Volume: 3 Issue: 1
  • Publication Date: 1990
  • Journal Name: Journal of Islamic Academy of Sciences
  • Journal Indexes: Sobiad Atıf Dizini
  • Page Numbers: pp.35-40
  • Gazi University Affiliated: No

Abstract

The toxicological studies performed on Bacillus isolate 310109 isolated from the Iskenderun region of Turkey, by experimental infection of mice have revealed the absence of acute and pro- longed toxicity. All acute and prolonged toxicity tests produced negative results with all the various routes, subcutaneous, intraperitoneal, intravenous injection oral (gavage), inhalation and percutaneous application and eye irritation test, using 2x108 bacteria per/ml suspension for each inoculation. Neither pathological symptoms nor mortality were observed. The behaviour and weight gain of the experimen- tally infected animals were within the normal range and close to those of the control animals.

Key Words: Safety tests, biological control, Bacillus thuringiensis.