Lack of association between the CYP11B2 gene polymorphism and preeclampsia, eclampsia, and the HELLP syndrome in Turkish women

PERÇİN, FERDA; Cetin, Meral; Pinarbasi, Ergun; Akgun, Egemen; Gurlek, Fatma; ÇETİN, ALİ

doi:10.1016/j.ejogrb.2005.08.030

Lack of association between the CYP11B2 gene polymorphism and preeclampsia, eclampsia, and the HELLP syndrome in Turkish women

PERÇİN F. E., Cetin M., Pinarbasi E., Akgun E., Gurlek F., ÇETİN A.

EUROPEAN JOURNAL OF OBSTETRICS & GYNECOLOGY AND REPRODUCTIVE BIOLOGY, vol.127, no.2, pp.213-217, 2006 (SCI-Expanded, Scopus)

Publication Type: Article / Article
Volume: 127 Issue: 2
Publication Date: 2006
Doi Number: 10.1016/j.ejogrb.2005.08.030
Journal Name: EUROPEAN JOURNAL OF OBSTETRICS & GYNECOLOGY AND REPRODUCTIVE BIOLOGY
Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
Page Numbers: pp.213-217
Gazi University Affiliated: Yes

Abstract

Objectives: It is possible that altered control of aldosterone synthase gene (CYP11B2) expression or translation may be responsible for. hypertension. Hypertension is one of the major components of preeclampsia. We present here a study investigating the association between the CYP11B2 gene polymorphism in the promoter region at the position of -344 and preeclampsia.