Partial External Biliary Diversion for Severe Diarrhea After Liver Transplant in Patients with Progressive Familial Intrahepatic Cholestasis Type 1

Düztaş D. T., SARI S., EĞRİTAŞ GÜRKAN Ö., SÖZEN M. H., DALGIÇ B., DALGIÇ A.

Experimental and Clinical Transplantation, vol.20, no.5, pp.81-84, 2022 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 20 Issue: 5
  • Publication Date: 2022
  • Doi Number: 10.6002/ect.pediatricsymp2022.o27
  • Journal Name: Experimental and Clinical Transplantation
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus, EMBASE, MEDLINE
  • Page Numbers: pp.81-84
  • Keywords: Bile acid, End-stage liver disease, Growth retardation, Hepatic steatosis
  • Gazi University Affiliated: Yes

Abstract

© Başkent University 2022 Printed in Turkey. All Rights Reserved.Progressive familial intrahepatic cholestasis is a heterogeneous group of autosomal recessive disorders, and liver transplant is the only curative treatment. A biliary diversion operation for disruption of enterohepatic circulation in patients with progressive familial intrahepatic cholestasis type 1 without cirrhosis is another option. We present a pediatric patient with progressive familial intrahepatic cholestasis type 1 who underwent liver transplant due to end-stage liver disease. After transplant, diarrhea and growth retardation complications resolved after partial external biliary diversion surgery.