<i>In silico</i> approach reveals <i>N</i>-(5-phenoxythiophen-2-yl)-2-(arylthio)acetamides as promising selective SIRT2 inhibitors: the case of structural optimization of virtual screening-derived hits

Gözelle M., Bakar Ateş F., Massarotti A., Ozkan E., Gunindi H. B., Özkan Y., ...More

JOURNAL OF BIOMOLECULAR STRUCTURE & DYNAMICS, vol.43, no.4, pp.1756-1767, 2025 (SCI-Expanded, Scopus) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 43 Issue: 4
  • Publication Date: 2025
  • Doi Number: 10.1080/07391102.2023.2293252
  • Journal Name: JOURNAL OF BIOMOLECULAR STRUCTURE & DYNAMICS
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus, BIOSIS, CAB Abstracts, Chemical Abstracts Core
  • Page Numbers: pp.1756-1767
  • Keywords: cytotoxicity, molecular modeling, SIRT2, thiophene, α-tubulin
  • Gazi University Affiliated: Yes

Abstract