Introduction: Angiogenesis is an important process after birth for neonates. Vascular endothelial growth factor is a potent proangiogenic protein, which stimulates endothelial cell proliferation, survival, and migration. For vessel maturation, all components have to move together. Angiopoietins (ANG) are very important signal proteins for pericytes and have not yet been determined in human breast milk. The aim of this study was to show whether there were ANG in human breast milk.