Fabrication of 2-mercaptobenzothiazole coated pencil graphite electrode for determination of Rutin

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En Nakra F., Uzun D., Hasdemir E.

3rd International Eurasian Conference onBiological and Chemical Sciences(EurasianBioChem 2020), 19 - 20 March 2020, pp.233

  • Publication Type: Conference Paper / Summary Text
  • Page Numbers: pp.233
  • Gazi University Affiliated: Yes



Flavonoids, a benzo-γ-pyrone derivatives, have received significant interest because they help treatment of health problems on human. Especially, rutin is important flavonoid present in plants, drinks and medicinal herbs [1]. Rutin (Ru) is known with its anti-bacterial, anti-inflammatory, anti-oxidation and anti-aging abilities [2]. So, it is necassary to develop a sensitive method to determine Ru in food and medicine. This study aims to fabricate a pencil graphite electrode (PGE) coated with 2-mercaptobenzothiazole using cyclic voltammetry (CV). This electrode was characterized by electrochemical impedance spectroscopy and used for determination of Ru by differential pulse voltammetry (DPV). Therefore, the effects of covering cycle, supporting electrolyte and pH were investigated to find optimum conditions. The modification procedure of PGE was performed between -1 and +2.0 V potential range with 15 CV at 100 mV s-1 scan rate. The fabricated electrode was successfully used to determine Ru in real samples. Keywords: Pencil graphite electrode, Flavonoids, Rutin, Voltammetry.