Clinical use of fresh-frozen plasma in neonatal intensive care unit

Altuntas N., Yenicesu I., BEKEN S., Kulali F., Belen F. B., HIRFANOĞLU İ. M., ...More

TRANSFUSION AND APHERESIS SCIENCE, vol.47, no.1, pp.91-94, 2012 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 47 Issue: 1
  • Publication Date: 2012
  • Doi Number: 10.1016/j.transci.2012.05.007
  • Journal Name: TRANSFUSION AND APHERESIS SCIENCE
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.91-94
  • Keywords: Neonate, Neonatal intensive care unit, Fresh frozen plasma, Hemorrhage, INTRAVENTRICULAR HEMORRHAGE, COAGULATION ABNORMALITIES, TRANSFUSION, COAGULOPATHY, HEMOSTASIS, NEWBORN, INFANTS, BIRTH
  • Gazi University Affiliated: Yes

Abstract

Recommendations for FFP use in neonates are based on a very limited amount of data, and not on well-designed randomized controlled trials. This retrospective study was performed to analyze our experience with FFP use in neonatal intensive care unit (NICU). From January 2006 until August 2011 a total of 80 neonates were identified as having been treated with FFP. The most common indication for FFP use was prolonged PT or aFTT, representing 32.8% of all usages of FFP. Following FFT treatment PT and aPTT normalized in 42% and 60% patients, respectively. Our results suggest that FFP were often used in acceptable indications in NICU. (C) 2012 Elsevier Ltd. All rights reserved.