Evaluation of perilipin 2 and melanocortin 5 receptor serum levels with sebogenesis in acne vulgaris patients

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Atıf İçin Kopyala

Orenay O. M., Sarifakioglu E., GÜLEKON A.

ACTA DERMATOVENEROLOGICA ALPINA PANNONICA ET ADRIATICA, cilt.30, sa.1, ss.7-9, 2021 (ESCI)

• Yayın Türü: Makale / Tam Makale
• Cilt numarası: 30 Sayı: 1
• Basım Tarihi: 2021
• Doi Numarası: 10.15570/actaapa.2021.2
• Dergi Adı: ACTA DERMATOVENEROLOGICA ALPINA PANNONICA ET ADRIATICA
• Derginin Tarandığı İndeksler: Emerging Sources Citation Index (ESCI), Scopus, EMBASE, MEDLINE
• Sayfa Sayıları: ss.7-9
• Gazi Üniversitesi Adresli: Evet

Özet

Introduction: Acne vulgaris is a multifactorial disease. One of the main factors that plays a role in acne pathogenesis is an increase in sebum secretion. For sebum secretion, sebocyte differentiation followed by sebogenesis is essential. Sebocyte differentiation and proliferation, and sebum synthesis are controlled by complex pathways. Studies have shown that perilipin 2 and melanocortin 5 receptors play a role in sebogenesis. This study sought to determine whether levels of perilipin 2 and melanocortin 5 receptors have an impact on the development of acne vulgaris.