The effects of epidural bupivacaine on ischemia/reperfusion-induced liver injury

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Sarikus Z., BEDİRLİ N., Yilmaz G., Bagriacik U., Bozkirli F.

BRATISLAVA MEDICAL JOURNAL-BRATISLAVSKE LEKARSKE LISTY, vol.117, no.1, pp.41-46, 2016 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 117 Issue: 1
  • Publication Date: 2016
  • Doi Number: 10.4149/bll_2016_009
  • Journal Name: BRATISLAVA MEDICAL JOURNAL-BRATISLAVSKE LEKARSKE LISTY
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.41-46
  • Keywords: thoracic epidural anesthesia, bupivacaine, ischemia reperfusion injury, liver, LOCAL-ANESTHETICS, BLOOD-FLOW, APOPTOSIS, ISCHEMIA, EXPRESSION, LIDOCAINE, ANALGESIA, SURVIVAL, MECHANISMS, ADHESION
  • Gazi University Affiliated: Yes

Abstract

BACKGROUND: Several animal studies showed beneficial effects of thoracic epidural anesthesia (TEA) in hippocampal, mesenteric and myocardial IR injury (2-4). In this study, we investigated the effects of epidural bupivacaine on hepatic ischemia reperfusion injury in a rat model.