Analysis of thiol/disulphide homeostasis and oxidant-antioxidant status as a result of exposure to radio-frequency electromagnetic fields


Yavas M. C., YEĞİN K., ORUÇ S., DELEN K., Sirav B.

ELECTROMAGNETIC BIOLOGY AND MEDICINE, cilt.40, sa.1, ss.84-91, 2021 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 40 Sayı: 1
  • Basım Tarihi: 2021
  • Doi Numarası: 10.1080/15368378.2021.1874970
  • Dergi Adı: ELECTROMAGNETIC BIOLOGY AND MEDICINE
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus, Academic Search Premier, BIOSIS, Compendex, EMBASE, MEDLINE
  • Sayfa Sayıları: ss.84-91
  • Anahtar Kelimeler: Antioxidant status, GSM-like, Oxidative stress, RF-EMFs, Thiol, disulphide homeostasis
  • Gazi Üniversitesi Adresli: Evet

Özet

The aim of the current study is to investigate the effect of daily long-term radio-frequency electromagnetic field (RF-EMFs) exposure on thiol/disulphide homeostasis and oxidant-antioxidant status in the serum of rats. Fourteen male Sprague Dawley rats were divided into two equal groups (n = 7). They were grouped as group 1 (sham-control) and group 2 (2100 MHz exposed). Group 2 rats were exposed to GSM-like signals for 5 h/day, 7 days per week for 14 days. In serum of blood samples, the native, total and native/total thiol levels and antioxidant-oxidant parameters were analyzed. The study revealed that the mean serum total thiol levels of GSM exposure group was rather higher than sham-control group (p = 0,219); the mean serum native thiol levels of GSM exposure group was rather higher than sham-control group (p = 0,416), and the mean serum disulphide levels of GSM exposure group was rather higher than sham-control group (p = 0,566). On the other hand, the mean serum total antioxidant status (TAS), total oxidant status (TOS) and oxidative stress index (OSI) of GSM exposure group were higher than sham-control group. There are no data in the literature, that examine the effects of RF-EMFs on thiol/disulphide homeostasis. The results of this study, indicate that RF-EMFs did not cause oxidative stress and statistically changes in thiol/disulphide homeostasis. More sample sizes and longer-term exposures are needed to confirm the results of this study.