Akademik Veri Yönetim Sistemi
25th European Congress on Obesity, Vienna, Austria, May 23-26, 2018, Vienna, Avusturya, 23 - 25 Mayıs 2018, ss.166
Introduction: Aging; is defined as the deterioration that occurs in physiological functions with the progress of age. The intestinal system consists of a complex structure of approximately 10¹³-10¹4
microorganisms.
Human intestinal microbiota has an important role in various metabolic, nutritional, physiological and immunological systems. Deterioration
in physiological functions with aging causes a decrease in microbial diversity, DNA damage, stress response and protection of the immune system in the intsetinal system. Aging also affects the gastrointestinal tract,
negatively affecting the hormones that control food intake, thus reducing
food intake. N Due to dietary differences, low-fat and high fiber content
polysaccharides from vegetable origin have led to high Firmicutes type
colonization, while animal fats containing high fat and low fiber content
have led to low Firmicutes type microorganism colonization in intestinal
microbiota. Aging is an effect on nutrient consumption, while nutrient
consumption affects on aging. For this reason, the consumption of nutrients, which are the most important components of microbiota, which
contains probiotic bacteria (probiotics) or nutrients (prebiotics) will enable the beneficial microorganisms to survive / multiply in microbiota and
consumption of high nutrients in the pulp content to provide short chain
fatty acid synthesis has become increasingly important in recent years.
This review was conducted to investigate the interaction between intestinal microbiota and healthy aging and to understand the relationship of
microbiota to nutrition and its effects on metabolism.
Methods: Literature review
Results: The microbiota that started to change with birth continues to
change until the age of adulthood and continues to change with the effect
of aging,
Conclusion: Aging is defined as the impairment of physiological functions with age progression. Aging is a period of increased sensitivity to
diseases. In the aging process, the bacterial composition and metabolic
functions change in the intestine. Probiotics, prebiotics and synbiotics exhibit the potential to alleviate gastrointestinal problems in older people
by modulating microbial activity and immune status. Probiotics are short
chain (oligosaccharides) carbohydrates with health-promoting effects in
the intestine. Prebiotics regulate the composition and balance in both the
lumenal and mucosal surfaces as a suitable living space for bifidobacteria
and lactobacilli in microbiota. Prebiotics also ffermentation short-chain
fatty acids in the colon to provide energy for the intestines and other body
tissues. As a result healthy microflora is resistant to intestinal infections
and shows immunomodulatory effect. Briefly, pro-prebiotics and synbiotics alleviate the defects caused by age and environmental effects in the
organism and play an important role in increasing the optimum quality
of life. Considering the elderly’s aging, difficulties in chewing and other
digestive problems, we think that the supplementation of pre-probiotic
and sinbiotics is important for the health of the intestinal microbiota by
the qualified professionals besides the adequate and balanced nutrition for
the optimum development of the intestinal microbiota