Tolmetin and salicylate therapy in acute rheumatic fever: Comparison of clinical efficacy and side-effects

Karademir S., Oguz D., Senocak F., Ocal B., Karakurt C., Cabuk F.

PEDIATRICS INTERNATIONAL, vol.45, no.6, pp.676-679, 2003 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 45 Issue: 6
  • Publication Date: 2003
  • Doi Number: 10.1111/j.1442-200x.2003.01801.x
  • Journal Name: PEDIATRICS INTERNATIONAL
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.676-679
  • Keywords: aspirin, rheumatic fever, tolmetin, ARTHRITIS, CHILDREN, GUIDELINES, NAPROXEN, ASPIRIN, DISEASE, SODIUM
  • Gazi University Affiliated: No

Abstract

Background: The arthritis of rheumatic fever is very responsive to treatment with salicylates, but there are many adverse reactions, especially hepatotoxicity, due to aspirin (acetylsalicylic acid) therapy. These side-effects change the course and duration of rheumatic fever. Other non-steroidal anti-inflammatory drugs may be equally effective, although no reports are available.