Successful Treatment of Paecilomyces variotii Peritonitis in a Liver Transplant Patient

Polat M., Kara S. S., TAPISIZ A., Demirtas Z., SARI S., KALKANCI A., ...Daha Fazla

MYCOPATHOLOGIA, cilt.179, sa.3-4, ss.317-320, 2015 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 179 Sayı: 3-4
  • Basım Tarihi: 2015
  • Doi Numarası: 10.1007/s11046-014-9854-1
  • Dergi Adı: MYCOPATHOLOGIA
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.317-320
  • Anahtar Kelimeler: Amphotericin B, Liver transplant, Paecilomyces variotii peritonitis, Voriconazole, VORICONAZOLE, COMBINATION
  • Gazi Üniversitesi Adresli: Evet

Özet

Paecilomyces variotii has previously been reported as a causative pathogen for peritonitis in patients on continuous ambulatory peritoneal dialysis and shown to be usually sensitive to amphotericin B and resistant to voriconazole. We report the first case, to our knowledge, of P. variotii peritonitis in a liver transplant patient, which was unresponsive to initial liposomal amphotericin B (L-AmB) treatment and resolved dramatically after the addition of voriconazole. The present case provides evidence for the clinical and microbiological effectiveness of voriconazole combined with L-AmB in treating P. variotii peritonitis refractory to initial L-AmB treatment.