Fluorescent and Biocompatible Nitrogen and Sulfur Co-Doped Carbon Nanodot as an Ocular Fundus Angiography Imaging Agent
Journal of Fluorescence, cilt.33, sa.5, ss.1917-1925, 2023 (SCI-Expanded, Scopus)
- Yayın Türü: Makale / Tam Makale
- Cilt numarası: 33 Sayı: 5
- Basım Tarihi: 2023
- Doi Numarası: 10.1007/s10895-023-03200-8
- Dergi Adı: Journal of Fluorescence
- Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus, Academic Search Premier, Biotechnology Research Abstracts, Chimica, Compendex, EMBASE, MEDLINE
- Sayfa Sayıları: ss.1917-1925
- Anahtar Kelimeler: Carbon nanodots, Fluorescence imaging, Fundus angiography
- Gazi Üniversitesi Adresli: Evet
Özet
The florescence characteristics and the toxicities of carbon nanodots (CDs) are directly related to their elemental compositions. Fluorescent and non-toxic agent for imaging of biological systems was aimed. Sulfur and nitrogen co-doped CDs (S/N-CDs) was hydrothermally produced in an average size of 8 nm. S/N-CDs showed blue fluorescence under UV-light with an excitation wavelength of 365 nm. After 24 h, S/N-CDs was non-cytotoxic in HUVEC and L929 cells. S/N-CDs have a great potential to act as an alternative material for commercial fluorescent materials with its 85.5% of quantum yield. S/N-CDs was approved in vitro as an imaging agent for an ocular fundus angiography of rats.