Crizotinib-induced toxicity in an experimental rat model

Gümüşay Ö., Esendagli-Yilmaz G., Üner A., Çetin B., Buyukberber S., Benekli M., ...More

WIENER KLINISCHE WOCHENSCHRIFT, vol.128, pp.435-441, 2016 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 128
  • Publication Date: 2016
  • Doi Number: 10.1007/s00508-016-0984-y
  • Journal Name: WIENER KLINISCHE WOCHENSCHRIFT
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.435-441
  • Keywords: Crizotinib, Rat, Toxicity, Pulmonary intraalveolar hemorrhage, CELL LUNG-CANCER, INDUCED ACUTE HEPATITIS, ALK INHIBITOR, MANAGEMENT, DIAGNOSIS, MUTATIONS, PATIENT, SAFETY
  • Gazi University Affiliated: Yes

Abstract

The aim of the present study was to evaluate the effect of crizotinib on visceral organs in an experimental rat model.