Validity of Biomarkers of Early Circulatory Impairment to Predict Outcome: A Retrospective Analysis

Carmen Bravo M., Lopez-Ortego P., Sanchez L., Madero R., Cabanas F., Koch A., ...More

FRONTIERS IN PEDIATRICS, vol.7, 2019 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 7
  • Publication Date: 2019
  • Doi Number: 10.3389/fped.2019.00212
  • Journal Name: FRONTIERS IN PEDIATRICS
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Keywords: transitional circulation, circulatory impairment, cardiovascular treatment, hypotension, preterm, VENA-CAVA FLOW, BIRTH-WEIGHT INFANTS, CAPILLARY REFILL, BLOOD-PRESSURE, CARDIOVASCULAR SUPPORT, CONTROLLED-TRIAL, PRETERM INFANTS, HYPOTENSION, AGE, NEURODEVELOPMENT
  • Gazi University Affiliated: Yes

Abstract

Objectives: The definition of circulatory impairment in the premature infant is controversial. Current research suggests overdiagnosis and overtreatment. We aimed to analyse which biomarkers move clinicians to initiate cardiovascular treatment (CVT). The prognostic capacity for adverse outcome (death and/or moderate-severe brain damage by cranial ultrasound at term equivalent) of these biomarkers was evaluated.