Demonstration of the DNA Integrity in Semen Samples with Normospermia, Oligozoospermia and Azoospermia by Comet Method and Immunohistochemical Determination of EGF-R and TGF-alpha

Baltaci E., Erdogan D., Kaplanoglu G.

GAZI MEDICAL JOURNAL, cilt.22, sa.2, ss.33-40, 2011 (ESCI) identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 22 Sayı: 2
  • Basım Tarihi: 2011
  • Doi Numarası: 10.5152/gmj.2011.08
  • Dergi Adı: GAZI MEDICAL JOURNAL
  • Derginin Tarandığı İndeksler: Emerging Sources Citation Index (ESCI), Scopus, TR DİZİN (ULAKBİM)
  • Sayfa Sayıları: ss.33-40
  • Anahtar Kelimeler: Comet, immunohistochemistry, semen, EGF-R, TGF-alpha
  • Gazi Üniversitesi Adresli: Evet

Özet

Objective: The aim of this study was to compare the rate of sperm cells with DNA damage by the comet assay, and to determine EGF-R and TGF-alpha localization by using immunohistochemical methods in normospermic, oligozoospermic and azoospermic events.