The effect of pneumoperitoneum on intravascular fibrinolytic activity in rats.

DİKMEN K., UĞRAŞ DİKMEN A., BOSTANCI H., KARAMERCAN A., Yagci M., AKIN M., ...More

Turkish journal of medical sciences, vol.46, no.5, pp.1528-1533, 2016 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 46 Issue: 5
  • Publication Date: 2016
  • Doi Number: 10.3906/sag-1501-53
  • Journal Name: Turkish journal of medical sciences
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus, TR DİZİN (ULAKBİM)
  • Page Numbers: pp.1528-1533
  • Keywords: Pneumoperitoneum, fibrinolysis, hypercoagulability, DEEP-VEIN THROMBOSIS, LAPAROSCOPIC CHOLECYSTECTOMY, OPEN SURGERY, COAGULATION, HEMOSTASIS, ACTIVATION, TRAUMA
  • Gazi University Affiliated: Yes

Abstract

Background/aim: Venous stasis during pneumoperitoneum in laparoscopic surgery is closely related to fibrin synthesis and deposition. The etiologic factors underlying fibrinolysis or hypercoagulability are not clearly defined. This study aimed to determine the effects of pneumoperitoneum time and pressure on coagulation cascade and the fibrinolytic pathway.