Plasma neutrophil gelatinase-associated lipocalin levels in acute myocardial infarction and stable coronary artery disease

ŞAHİNARSLAN A., Kocaman S. A., Bas D., Akyel A., Ercin U., Zengin O., ...More

CORONARY ARTERY DISEASE, vol.22, no.5, pp.333-338, 2011 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 22 Issue: 5
  • Publication Date: 2011
  • Doi Number: 10.1097/mca.0b013e3283472a71
  • Journal Name: CORONARY ARTERY DISEASE
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.333-338
  • Keywords: biomarkers, inflammation, ischemic heart disease, myocardial infarction, plaque instability, C-REACTIVE PROTEIN, CONTRAST NEPHROPATHY, LEUKOCYTE ACTIVATION, HEART-DISEASE, SEVERITY, NGAL, MATRIX-METALLOPROTEINASE-9, ATHEROSCLEROSIS, INTERVENTIONS, PLAQUES
  • Gazi University Affiliated: Yes

Abstract

Introduction Inflammation and polymorphonuclear neutrophils are shown to be important in the pathogenesis of acute myocardial infarction (AMI). Neutrophil gelatinase-associated lipocalin (NGAL) is secreted from neutrophils and may increase the proteolytic activity within the atherosclerotic plaque. We aimed to investigate whether the plasma levels of NGAL are higher in patients with AMI compared with stable coronary artery disease (CAD).