ALTERATION BY ILOPROST OF THE VASOSPASTIC EFFECTS OF ENDOTHELIN-1 IN RABBIT CEREBRAL VESSELS

KESKIL I., BAYKANER M., SENCER H., ATAOGLU O., ILGIT E. T., ERDOGAN B., ...Daha Fazla

NEUROREPORT, cilt.5, sa.9, ss.1089-1092, 1994 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 5 Sayı: 9
  • Basım Tarihi: 1994
  • Doi Numarası: 10.1097/00001756-199405000-00017
  • Dergi Adı: NEUROREPORT
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.1089-1092
  • Gazi Üniversitesi Adresli: Evet

Özet

THE reversal of endothelin-1 induced cerebral vasospasm with Iloprost was studied in the rabbit. Vasospasm in the basilar artery was evaluated by angiography; cerebral ischaemia by 'red-neurone-count' on light microscopy and morphological changes by electron microscopy. A potent antagonistic effect of Iloprost against ET-1 was observed in each of the parameters measured.