Use of long-term combined therapy with inhaled iloprost and oral sildenafil in an adult patient with Eisenmenger syndrome

Okyay K., CEMRİ M., Boyaci B., Yalcin R., Cengel A.

Cardiology in Review, vol.13, no.6, pp.312-314, 2005 (SCI-Expanded) identifier identifier

  • Publication Type: Article / Article
  • Volume: 13 Issue: 6
  • Publication Date: 2005
  • Doi Number: 10.1097/01.crd.0000181618.29506.1e
  • Journal Name: Cardiology in Review
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.312-314
  • Gazi University Affiliated: Yes


Eisenmenger syndrome is characterized by elevated pulmonary vascular resistance and right-to-left shunting of blood through a systemic to pulmonary circulation connection. Treatment requires either lung transplantation with intracardiac repair or heart-lung transplantation. There are inadequate data regarding treatment alternatives when the patient is not a candidate for surgery. In this article, we report on the case of a 68-year-old woman with Eisenmenger syndrome related to congenital heart disease who was treated with inhaled iloprost and oral sildenafil for 2 years. Copyright © 2005 by Lippincott Williams & Wilkins.