Synthesis and chemical transformations of 3-acetyl-4-hydroxyquinolin-2(1H)-one and its N-substituted derivatives: bird's eye view

Abdou M. M., SEFEROĞLU Z., Fathy M., Akitsu T., Koketsu M., Kellow R., ...More

RESEARCH ON CHEMICAL INTERMEDIATES, vol.45, no.3, pp.919-934, 2019 (SCI-Expanded) identifier identifier

  • Publication Type: Article / Review
  • Volume: 45 Issue: 3
  • Publication Date: 2019
  • Doi Number: 10.1007/s11164-018-3652-1
  • Journal Name: RESEARCH ON CHEMICAL INTERMEDIATES
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.919-934
  • Keywords: 3-Acetyl-4-hydroxyquinolin-2(1H)-one, Synthesis, Chemical reactivity, Condensation, Cyclization, Heterocycles, PHOTO-ANTIPROLIFERATIVE ACTIVITY, RING-CLOSURE REACTIONS, QUINOLINE DERIVATIVES, GLYCINE SITE, HETEROCYCLIZATION REACTIONS, ANTIMICROBIAL EVALUATION, STRUCTURAL DETERMINATION, POTENTIAL ANTIBACTERIAL, BIOLOGICAL EVALUATION, TAUTOMERIC STRUCTURE
  • Gazi University Affiliated: Yes

Abstract

The chemistry of 3-acetyl-4-hydroxyquinolin-2(1H)-ones has attracted increased attention in both synthetic organic and medicinal chemistry, as numerous advancements in the use of this family of important compounds seems to be of considerable value. This account summarizes the results from the literature focusing on synthesis of 3-acetyl-4-hydroxyquinolin-2(1H)-ones as well as their reactions are also discussed.