2-{2-[4-(4-Fluorophenyl)piperazin-1-yl]-2-oxoethyl}-6-(morpholin-4-yl)-4-phenylpyridazin-3(2H)-one


AYDIN A., Sukuroglu M. K. , AKKURT M., BÜYÜKGÜNGÖR O.

ACTA CRYSTALLOGRAPHICA SECTION E-STRUCTURE REPORTS ONLINE, vol.67, 2011 (Peer-Reviewed Journal) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 67
  • Publication Date: 2011
  • Doi Number: 10.1107/s1600536811005071
  • Journal Name: ACTA CRYSTALLOGRAPHICA SECTION E-STRUCTURE REPORTS ONLINE
  • Journal Indexes: Science Citation Index Expanded, Scopus

Abstract

In the title compound, C26H28FN5O3, the morpholine ring adopts a chair conformation. The piperazine ring is puckered [Q(T) = 0.5437 (15) angstrom, theta = 8.89 (15) and phi = 357.2 (11)degrees]. The 1,6-dihydropyridazine ring makes dihedral angles of 28.03 (7) and 77.46 (7)degrees with the phenyl and benzene rings, respectively. In the crystal, molecules are linked along the c axis by C-H center dot center dot center dot O interactions and are flattened parallel to the ac plane. C-H center dot center dot center dot pi interactions also contribute to the stability of the structure.