Prediction of IDH Mutation Status in High-grade Gliomas Using DWI and High T1-weight DSC-MRI.

Cindil E., Sendur H. N. , Cerit M. N. , Erdogan N., Celebi F., Dag N., ...More

Academic radiology, vol.29, 2022 (Peer-Reviewed Journal) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 29
  • Publication Date: 2022
  • Doi Number: 10.1016/j.acra.2021.02.002
  • Journal Name: Academic radiology
  • Journal Indexes: Science Citation Index Expanded, Scopus, CINAHL, EMBASE, MEDLINE
  • Keywords: High-grade glioma, Isocitrate dehydrogenase mutation, Cerebral blood volume (CBV), Percentage signal recovery (PSR), Diffusion weighted imaging (DWI), Dynamic susceptibility contrast-enhanced MR imaging (DSC-MRI), DYNAMIC-SUSCEPTIBILITY CONTRAST, CEREBRAL BLOOD-VOLUME, CENTRAL-NERVOUS-SYSTEM, LEAKAGE-CORRECTION, HISTOGRAM ANALYSIS, DIFFUSE GLIOMAS, PERFUSION, TUMOR, CLASSIFICATION, SURVIVAL


Rationale and Objectives: We aimed to evaluate the diagnostic performance of diffusion-weighted imaging (DWI) and dynamic susceptibility contrast-enhanced (DSC) magnetic resonance imaging (MRI) parameters in the noninvasive prediction of the isocitrate dehydrogenase (IDH) mutation status in high-grade gliomas (HGGs).