Evaluation of isotretinoin effects on depression, sleep apnea and sleep quality

Orenay O. M., TEMEL B., Capci A. K., Bal Z. I., Karaosmanoglu N.

CUTANEOUS AND OCULAR TOXICOLOGY, cilt.43, sa.2, ss.129-133, 2024 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 43 Sayı: 2
  • Basım Tarihi: 2024
  • Doi Numarası: 10.1080/15569527.2024.2340435
  • Dergi Adı: CUTANEOUS AND OCULAR TOXICOLOGY
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus, BIOSIS, CAB Abstracts, EMBASE, Environment Index, MEDLINE, Veterinary Science Database
  • Sayfa Sayıları: ss.129-133
  • Gazi Üniversitesi Adresli: Hayır

Özet

BackgroundIsotretinoin is used to treat severe acne, treatment-resistant moderate acne, and acne that leads to scarring or psychological distress. It has many side effects and is also associated with depression, sleep apnea, and sleep disturbances.ObjectivesIn this study, we aimed to evaluate the effects of isotretinoin on depression, sleep apnea, and sleep quality.MethodsA total of 42 patients diagnosed with acne and started isotretinoin treatment were included in the study. In order to compare the effects of isotretinoin, patients were asked to fill out a questionnaire containing the Beck Depression Inventory (BDI), the Berlin Questionnaire (BQ), and the Pittsburg Sleep Quality Index (PSQI) at baseline and third months of treatment.ResultsThere was no statistically significant difference in BDI, BQ, and PSQI scores between the 1st and 3rd months of treatment (p = .53, p = .5, p = .35).ConclusionThis study showed that isotretinoin had no significant effects on depression and sleep quality.