Targeting Cancer Cell Metabolism with Metformin, Dichloroacetate and Memantine in Glioblastoma (GBM)

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Albayrak G., KONAÇ E., Dere U. A., Emmez H.

TURKISH NEUROSURGERY, cilt.31, sa.2, ss.233-237, 2021 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 31 Sayı: 2
  • Basım Tarihi: 2021
  • Doi Numarası: 10.5137/1019-5149.jtn.29176-20.3
  • Dergi Adı: TURKISH NEUROSURGERY
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus, EMBASE, MEDLINE
  • Sayfa Sayıları: ss.233-237
  • Anahtar Kelimeler: Glioblastoma, Cancer cell, Metabolism, Metformin, Dichloroacetate, Memantine
  • Gazi Üniversitesi Adresli: Evet

Özet

AIM: To investigate the effects of metformin, dichloroacetate (DCA), and memantine on T98G and U87-MG human glioblastoma (GBM) cells to target tumor cell metabolism in a multi-directional manner.