Effects of Scaling and Root Planing and Subantimicrobial Dose Doxycycline on Gingival Crevicular Fluid Levels of Matrix Metalloproteinase-8, -13 and Serum Levels of HsCRP in Patients With Chronic Periodontitis

TÜTER G., SERDAR M. A., Kurtis B., Walker S. G., Atak A., Toyman U., ...More

JOURNAL OF PERIODONTOLOGY, vol.81, no.8, pp.1132-1139, 2010 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 81 Issue: 8
  • Publication Date: 2010
  • Doi Number: 10.1902/jop.2010.090694
  • Journal Name: JOURNAL OF PERIODONTOLOGY
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.1132-1139
  • Keywords: C-reactive protein, doxycycline, gingival crevicular fluid, matrix metalloproteinases, periodontitis, treatment, C-REACTIVE PROTEIN, ADULT PERIODONTITIS, CLINICAL-PARAMETERS, THERAPY, DISEASE, MARKERS, TISSUE, INHIBITOR, INFLAMMATION, PREVENTION
  • Gazi University Affiliated: Yes

Abstract

Background: This study evaluates the efficacy of subanti-microbial dose doxycycline (SDD) in conjunction with scaling and root planing (SRP) on gingival crevicular fluid (GCF) levels of matrix metalloproteinase (MMP)-8 and -13 and on serum levels of high-sensitivity C-reactive protein (HsCRP) in patients with chronic periodontitis (CP).